An open label, single arm, multi-centre, phase 2 trial of lenvatinib for the treatment of anaplastic thyroid cancer (ATC)

3 UK centres are being opened:

The Royal Marsden Hospital: London (Dr Kate Newbold)

Velindre Cancer Centre: Cardiff (Dr Laura Moss)

Beatson West of Scotland Cancer Centre: Glasgow (Prof Nick Reed)

The iNATT project was presented at a number of national and international meetings in 2015.

• EORTC Endocrine Task Force, Brussels
• ITOG (International Thyroid Oncology Group), Rome
• Joint BAETS and UKEPS (British Association Endocrine and Thyroid Surgeons, UK Endocrine Pathology Society), Henley
• International Thyroid Congress, Orlando
• Nordic Thyroid Oncology Group, Copenhagen

iNATT - interNational Anaplastic Thyroid Cancer Tissue Bank and Database Project - launched a new website in March 2016 to encourage clinicians and researchers to share information about Anaplastic Thyroid Cancer.

The website has been developed in order to promote the iNATT project as well as a means to try and raise the profile of anaplastic thyroid cancer for patients, clinicians and researchers. The website therefore includes information on other research projects and links to information resources.

The interNational Anaplastic Thyroid Cancer Tissue Bank and Database project (iNATT) was launched in 2013.

The project was initially launched in the UK in 2013 and then obtained ethical approval to be extended internationally in 2014.

iNATT offers patients with this diagnosis a rare opportunity to participate in research. We hope to learn more about why and how this type of cancer develops so that we can then develop new ways to treat it. This is going to be a long term project which will need to run over a number of years.

The research project is run by Dr Laura Moss, Consultant Oncologist at Velindre Cancer Centre, Cardiff, UK in conjunction with the staff of the Wales Cancer Bank, a multidisciplinary steering committee and with the support of the National Cancer Research Institute Thyroid Cancer Subgroup.

The project also has the support of the UK Endocrine Pathology Society, the International Rare Cancer Initiative, members of Thyroid Cancer Forum-UK and the European Thyroid Association along with thyroid cancer patient charity support from Thyroid Cancer Support Group-Wales and the Butterfly Thyroid Cancer Trust.

Funding has been provided by Thyroid Cancer Support Group Wales (registered charity number 1113774).

If you would like to find out more about iNATT please contact the Chief Investigator via Laura.Moss@wales.nhs.uk or +44 (0) 29 20316205

Clinical Trial Now Open in UK

iNATT Launched in 2013

iNATT Presentations 2015

iNATT Website Launched in 2016